The efficacy of AFI for assessing UC activity was reviewed. AFI images of UC lesions could be classified into 4 categories; Green, Green with Purple Spots, Purple with Green Spots, Purple. The strength of purple in AFI images of UC lesions is related to histologic severity, thus this classification is helpful to assess the activity of UC. We also quantified the auto-fluorescence of AFI images using color analysis software. Active lesions showed significantly low auto-florescence / reflex ration rather than inactive area in UC patients. The ratio is inversely proportional to histologic severity. When defining the cut-off value as 0.9, the accuracy to predict histologic activity by AFI is 92%.
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