Atypical tumour-like involvement of the colon in secondary systemic amyloidosis which vanished after 1 month of observation
著者
安藤, 勝祥
(Ando, Katsuyoshi)
Fujiya, Mikihiro
Ito, Takahiro
Sugiyama, Ryuji
Nata, Toshie
Nomura, Yoshiki
Ueno, Nobuhiro
Kashima, Shin
Ishikawa, Chisato
Inaba, Yuhei
Moriichi, Kentaro
Okamoto, Kotaro
Ikuta, Katsuya
Mizukami, Yusuke
Tokusashi, Yoshihiko
Miyokawa, Naoyuki
Watari, Jiro
Kohgo, Yutaka
上位タイトル
BMJ Case Reports
Vol.2011,
(2011.
01)
識別番号
ISSN
1757-790X
DOI
10.1136/bcr.01.2011.3775
抄録
Amyloidosis occurs as a result of the extracellular deposition of protein fibrils in organs and tissues, thus causing mild to severe pathophysiological changes. The gastrointestinal tract is a common site of amyloid deposition. While intestinal amyloidosis frequently results in polypoid lesions, ulcerations, nodules and petechial mucosal haemorrhage, tumour-like lesions are rarely developed and infrequently diagnosed before the resection because of the difficulty in differentiating them from colon cancer. The authors herein reported a case of intestinal amyloid A amyloidosis with a complication of a tumour-like lesion endoscopically resembling a malignant lesion, which was completely diminished after 1 month of observation with bowel rest. Such conservative treatment is a feasible option to cure intestinal tumour-like lesions in patients with intestinal amyloidosis when no neoplastic change is histologically detected, possibly decreasing the need for surgery of the fragile mucosa.
