Alpha-fetoprotein-producing primary lung carcinoma : A case report
著者
北田, 正博
(Kitada, Masahiro)
Ozawa, Keisuke
Sato, Kazuhiro
Matsuda, Yoshinari
Hayashi, Satoshi
Tokusashi, Yoshihiko
Miyokawa, Naoyuki
Sasajima, Tadahiro
上位タイトル
World Journal of Surgical Oncology
Vol.9,
(2011.
5)
,p.47-1-
47-4
識別番号
ISSN
1477-7819
DOI
10.1186/1477-7819-9-47
抄録
Alpha-fetoprotein (AFP)-producing lung adenocarcinoma is a rare type of lung cancer, with its characteristics not yet fully clarified. We recently encountered a case of this type of lung cancer. The patient was a 69-year-old man who consulted an internist with the chief complaint of epigastric pain. Chest X-ray and CT revealed a lobulated mass measuring 70 mm in diameter in the right lower lung field and a metastasis in the right hilar lymph nodes. Of the tumor markers, the serum AFP was elevated (4620 ng/ml), and the serum carcinoembryonic antigen and carbohydrate antigen 19-9 were also slightly elevated. Transbronchial lung biopsy revealed the diagnosis of lung cancer. Under thoracoscopic assistance, right lower lobectomy + mediastinal lymph node dissection was carried out. Immunostaining showed the tumor cells to be AFP-positive. The tumor was thus diagnosed as an AFP-producing lung adenocarcinoma. The patient followed an uneventful clinical course after the surgery, with serum AFP decreasing to the normal range by about 2 weeks after the surgery. As of this writing, no sign of tumor recurrence has been noted. This case is presented here with a review of the literature.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
