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AMCoR:Asahikawa Medical University Collection and Research (旭川医科大学学術成果リポジトリ)は、本学で生産された電子的な知的生産物(学術雑誌論文の原稿・教材・学術資料など)を保存し、原則的に無償で発信するためのインターネット上の保管庫です。

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ID PR-Aburano
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タイトル Impaired cardiac sympathetic nerve function in patients with Kawasaki disease: comparison with myocardial perfusion
著者
油野, 民雄 (Aburano, Tamio)
Shuke, N
Yamamoto, W
Okizaki, A
Sato, J
Kajino, H
Fujieda, K
上位タイトル
Pediatric Research Vol.57, No.5 Pt 1  (2005. 5) ,p.744- 748
識別番号
ISSN
0031-3998
URI http://journals.lww.com/pedresearch/Fulltext/2005/05010/Impaired_Cardiac_Sympathetic_Nerve_Function_in.23.aspx
抄録 Kawasaki disease (KD) is a leading cause of CAD in children. The impairment of cardiac sympathetic nerve function (CSNF) in the adult patients with coronary artery disease (CAD) could often be seen. However, little is known concerning the impairment of CSNF in KD patients. We investigated CSNF and its relationship with myocardial perfusion in KD patients. Eleven children with KD and 4 controls were studied with 123I-metaiodobenzylguanidine (MIBG) and stressed 201Tl single photon emission computed tomography. By the findings on coronary artery angiography (CAG), the patients were divided into 2 groups: A, without stenosis; B, with significant stenosis and/or old myocardial infarction. CSNF was evaluated from the uptake of 123I-MIBG. While myocardial perfusion was evaluated from 201Tl uptake. The numbers of patients in the groups A and B were 7 and 4. Perfusion defect was found in 0, and 2 patients in group A (0%), and B (50%). 123I-MIBG defects were found in 1 and 4 patients in the group A (14%) and B (100%). There were excellent concordances between the finding of 201Tl and 123I-MIBG in group A. While in group B, the coronary territories with 123I-MIBG defects were significantly more than those with perfusion defects (p < 0.05). In KD patients, the impairment of CSNF might be subsequent to coronary artery stenosis and was more severe than the injury of myocardial perfusion.
注記 This is a non-final version of an article published in final form in Zhao, Chunlei ; Shuke, Noriyuki ; Yamamoto, Wakako ; Okizaki, Atsutaka ; Sato, Junichi ; Kajino, Hiroki ; Fujieda, Kenji ; Aburano, Tamio, Impaired cardiac sympathetic nerve function in patients with Kawasaki disease: comparison with myocardial perfusion, Pediatric research 57(5 pt1), 2005, pp. 744-748
言語
eng
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ジャンル Journal Article
著者版フラグ author
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/ Public / 国外雑誌論文
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